Health Minister Nina Warken is the frontrunner to lead the chancellery, a move that would elevate the longtime party loyalist to a central administrative position. To maintain balance, Thorsten Frei, who currently manages government coordination, is expected to transition into Spahn's former role as head of the CDU/CSU parliamentary faction. Meanwhile, Carsten Linnemann, the CDU secretary general, is being eyed as the successor for the health ministry. Reports also suggest that lawmaker Philipp Amthor may join the chancellery team as minister of state to oversee federal relations with Germany's 16 states.

While these names circulate, officials emphasize that negotiations remain fluid. The departure of Spahn, once considered a viable internal rival to Merz, followed his public disclosure regarding a child born via surrogate in the United States—a practice that clashes with the official stance of his party. With the coalition facing significant scrutiny during its inaugural year, the stability of these appointments is critical to maintaining Merz’s legislative agenda.