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Oracle and Buck Institute Launch Initiative to Predict Age-Related Decline

The Buck Institute for Research on Aging is partnering with Oracle to leverage a massive repository of 122 million longitudinal health records. This collaboration seeks to transform aging research into a predictive science by developing an FDA-grade "Intrinsic Capacity Score" to identify health declines years before they manifest.

Oracle and Buck Institute Launch Initiative to Predict Age-Related Decline
Photo: Bio & News

The initiative serves as a core analytics engine for the Stanford-led THRIVE consortium, a project funded by the U.S. government’s ARPA-H agency. By applying advanced AI-driven analytics to real-world patient data, researchers aim to move beyond reactive care. The goal is to construct statistically validated models that flag subtle clinical shifts, allowing for earlier interventions in patients at the highest risk for frailty and chronic illness.

Dr. David Furman of the Buck Institute noted that the complexity of modern aging research requires accessible, high-depth patient data to bridge the gap between early clinical signals and long-term health outcomes. The Oracle Life Sciences Data Intelligence platform provides the researchers with a cloud-native workspace, enabling them to build cohorts and run bioinformatics workflows without the bottleneck of traditional data preparation. This infrastructure is intended to accelerate the transition from scientific hypothesis to clinical trial readiness, ultimately aiming to reshape how medicine addresses the biological processes of aging.

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