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Sagent Pharmaceuticals Releases First Ready-to-Use ICG Injection

Sagent Pharmaceuticals has launched Zyogreen, the first FDA-approved ready-to-use indocyanine green injection available in the U.S. market. By eliminating the time-consuming reconstitution process required for traditional lyophilized powders, the sterile solution offers surgical and imaging teams a more efficient option for fluorescence-guided procedures and diagnostic mapping.

Sagent Pharmaceuticals Releases First Ready-to-Use ICG Injection
Photo: Bio & News

The commercial rollout follows a distribution agreement with Provepharm, a firm specializing in medical and diagnostic dyes. The U.S. market for indocyanine green reached approximately $128 million for the twelve months ending in July 2026, according to IQVIA data. This product joins Bludigo in Sagent’s growing portfolio of surgical visualization tools.

Zyogreen is indicated for a range of clinical applications, including vascular and gastrointestinal surgery, organ transplants, and lymphatic mapping in oncology. Unlike conventional formulations that require preparation at the point of care, this sterile liquid is designed to streamline workflows in operating rooms. The product is suitable for adults and specific pediatric age groups for biliary duct visualization. Sagent is currently distributing the agent through its nationwide network, aiming to improve reliability for hospitals and health systems.

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